2021 Big 12 Conference Leaders Penalties - Games vs. FBS non-Power 5 Conference Teams Only through 01/10/2022
| Name | G | Pen. | Yards | Pen./G | Yards/G | |
|---|---|---|---|---|---|---|
| 1 | Texas | 2 | 9 | 76 | 4.5 | 38.0 |
| 2 | Kansas | 1 | 6 | 43 | 6.0 | 43.0 |
| 3 | Kansas State | 1 | 6 | 45 | 6.0 | 45.0 |
| 4 | Baylor | 2 | 11 | 99 | 5.5 | 49.5 |
| 5 | Oklahoma | 1 | 7 | 50 | 7.0 | 50.0 |
| 6 | Oklahoma State | 3 | 16 | 155 | 5.3 | 51.7 |
| 7 | Iowa State | 1 | 7 | 52 | 7.0 | 52.0 |
| 8 | Texas Tech | 2 | 15 | 122 | 7.5 | 61.0 |
| 8 | TCU | 1 | 9 | 61 | 9.0 | 61.0 |