2021 Big 12 Conference Leaders Penalties - Games in August/September Only through 01/10/2022
| Name | G | Pen. | Yards | Pen./G | Yards/G | |
|---|---|---|---|---|---|---|
| 1 | Texas | 4 | 18 | 127 | 4.5 | 31.8 |
| 2 | Iowa State | 4 | 18 | 133 | 4.5 | 33.3 |
| 3 | TCU | 3 | 20 | 165 | 6.7 | 55.0 |
| 4 | Kansas | 4 | 20 | 179 | 5.0 | 44.8 |
| 5 | West Virginia | 4 | 26 | 203 | 6.5 | 50.8 |
| 6 | Kansas State | 4 | 24 | 204 | 6.0 | 51.0 |
| 7 | Oklahoma | 4 | 24 | 216 | 6.0 | 54.0 |
| 8 | Texas Tech | 4 | 28 | 251 | 7.0 | 62.8 |
| 9 | Oklahoma State | 4 | 30 | 257 | 7.5 | 64.3 |
| 10 | Baylor | 4 | 28 | 276 | 7.0 | 69.0 |