2021 Big 12 Conference Leaders Rushing Offense - Games in August/September Only through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Texas | 4 | 176 | 1071 | 6.09 | 15 | 44.00 | 267.75 |
| 2 | Baylor | 4 | 166 | 1093 | 6.58 | 12 | 41.50 | 273.25 |
| 3 | Kansas State | 4 | 153 | 739 | 4.83 | 11 | 38.25 | 184.75 |
| 4 | Oklahoma | 4 | 136 | 644 | 4.74 | 10 | 34.00 | 161.00 |
| 4 | Texas Tech | 4 | 126 | 640 | 5.08 | 10 | 31.50 | 160.00 |
| 6 | West Virginia | 4 | 138 | 493 | 3.57 | 9 | 34.50 | 123.25 |
| 7 | TCU | 3 | 118 | 619 | 5.25 | 7 | 39.33 | 206.33 |
| 7 | Iowa State | 4 | 138 | 623 | 4.51 | 7 | 34.50 | 155.75 |
| 7 | Oklahoma State | 4 | 171 | 573 | 3.35 | 7 | 42.75 | 143.25 |
| 10 | Kansas | 4 | 152 | 570 | 3.75 | 5 | 38.00 | 142.50 |