2021 Big 12 Conference Leaders Tackles For Loss - Games vs. Ranked Teams Only (AP Poll) through 01/10/2022
| Name | G | TFL | TFL Yards | TFL/G | |
|---|---|---|---|---|---|
| 1 | Baylor | 5 | 42.0 | 220 | 8.40 |
| 2 | Oklahoma State | 4 | 34.0 | 153 | 8.50 |
| 3 | Iowa State | 5 | 36.0 | 128 | 7.20 |
| 4 | Texas | 5 | 33.0 | 101 | 6.60 |
| 5 | Oklahoma | 3 | 25.0 | 84 | 8.33 |
| 6 | Texas Tech | 4 | 21.0 | 82 | 5.25 |
| 7 | Kansas State | 3 | 20.0 | 76 | 6.67 |
| 8 | TCU | 3 | 15.0 | 50 | 5.00 |
| 9 | West Virginia | 3 | 12.0 | 39 | 4.00 |
| 10 | Kansas | 3 | 12.0 | 38 | 4.00 |