2021 Big 12 Conference Leaders Rushing Offense - Games vs. Non-Conference Teams Only through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Baylor | 4 | 176 | 1245 | 7.07 | 12 | 44.00 | 311.25 |
| 2 | Oklahoma State | 4 | 172 | 670 | 3.90 | 6 | 43.00 | 167.50 |
| 3 | Kansas State | 4 | 162 | 860 | 5.31 | 14 | 40.50 | 215.00 |
| 4 | Oklahoma | 4 | 151 | 909 | 6.02 | 13 | 37.75 | 227.25 |
| 5 | Texas Tech | 4 | 137 | 772 | 5.64 | 11 | 34.25 | 193.00 |
| 6 | West Virginia | 4 | 136 | 492 | 3.62 | 9 | 34.00 | 123.00 |
| 7 | Texas | 3 | 124 | 735 | 5.93 | 11 | 41.33 | 245.00 |
| 8 | Kansas | 3 | 119 | 461 | 3.87 | 5 | 39.67 | 153.67 |
| 8 | Iowa State | 4 | 119 | 473 | 3.97 | 5 | 29.75 | 118.25 |
| 10 | TCU | 3 | 118 | 619 | 5.25 | 7 | 39.33 | 206.33 |