2021 Big 12 Conference Leaders Scoring Defense - Games vs. FBS (I-A) Teams Only through 01/10/2022
| Name | G | TD | FG | 1XP | 2XP | Safety | Points | Points/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Oklahoma State | 13 | 29 | 11 | 28 | 0 | 1 | 237 | 18.2 |
| 1 | Baylor | 13 | 28 | 18 | 27 | 0 | 0 | 249 | 19.2 |
| 1 | Kansas State | 12 | 28 | 18 | 26 | 0 | 1 | 250 | 20.8 |
| 1 | Iowa State | 12 | 33 | 9 | 32 | 0 | 0 | 257 | 21.4 |
| 1 | Texas Tech | 12 | 48 | 11 | 47 | 0 | 1 | 370 | 30.8 |
| 1 | Kansas | 11 | 66 | 10 | 66 | 0 | 0 | 492 | 44.7 |
| 7 | TCU | 11 | 55 | 12 | 48 | 1 | 0 | 416 | 37.8 |
| 8 | West Virginia | 12 | 36 | 19 | 33 | 2 | 0 | 310 | 25.8 |
| 8 | Oklahoma | 12 | 43 | 12 | 37 | 2 | 0 | 335 | 27.9 |
| 8 | Texas | 12 | 44 | 22 | 39 | 2 | 0 | 373 | 31.1 |