2021 Big 12 Conference Leaders Passing Defense - Games vs. FBS (I-A) Teams Only through 01/10/2022
| Name | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Oklahoma State | 13 | 411 | 238 | 57.9 | 2709 | 6.6 | 16 | 9 | 121.74 | 31.6 | 208.4 |
| 2 | Baylor | 13 | 422 | 255 | 60.4 | 3072 | 7.3 | 13 | 19 | 122.75 | 32.5 | 236.3 |
| 3 | Iowa State | 12 | 315 | 192 | 61.0 | 2205 | 7.0 | 18 | 9 | 132.90 | 26.3 | 183.8 |
| 4 | Texas | 12 | 377 | 255 | 67.6 | 2688 | 7.1 | 16 | 7 | 137.83 | 31.4 | 224.0 |
| 5 | Kansas State | 12 | 349 | 242 | 69.3 | 2622 | 7.5 | 15 | 10 | 140.90 | 29.1 | 218.5 |
| 6 | West Virginia | 12 | 347 | 225 | 64.8 | 2690 | 7.8 | 17 | 9 | 140.94 | 28.9 | 224.2 |
| 7 | Oklahoma | 12 | 409 | 272 | 66.5 | 3280 | 8.0 | 26 | 10 | 149.96 | 34.1 | 273.3 |
| 8 | Texas Tech | 12 | 396 | 262 | 66.2 | 3144 | 7.9 | 28 | 10 | 151.13 | 33.0 | 262.0 |
| 9 | TCU | 11 | 296 | 195 | 65.9 | 2801 | 9.5 | 20 | 9 | 161.59 | 26.9 | 254.6 |
| 10 | Kansas | 11 | 292 | 211 | 72.3 | 2739 | 9.4 | 27 | 7 | 176.78 | 26.5 | 249.0 |