2021 Big 12 Conference Leaders Scoring Defense - Games in December/January Only through 01/10/2022
| Name | G | TD | FG | 1XP | 2XP | Safety | Points | Points/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Texas Tech | 1 | 1 | 0 | 1 | 0 | 0 | 7 | 7.0 |
| 2 | Baylor | 2 | 2 | 3 | 2 | 0 | 0 | 23 | 11.5 |
| 2 | West Virginia | 1 | 2 | 1 | 1 | 1 | 0 | 18 | 18.0 |
| 2 | Iowa State | 1 | 2 | 2 | 2 | 0 | 0 | 20 | 20.0 |
| 5 | Kansas State | 1 | 3 | 0 | 2 | 0 | 0 | 20 | 20.0 |
| 6 | Oklahoma | 1 | 4 | 1 | 3 | 1 | 0 | 32 | 32.0 |
| 7 | Oklahoma State | 2 | 8 | 0 | 8 | 0 | 0 | 56 | 28.0 |