2021 Big 12 Conference Leaders Scoring Defense - Games in November Only through 01/10/2022
| Name | G | TD | FG | 1XP | 2XP | Safety | Points | Points/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Oklahoma State | 4 | 6 | 3 | 6 | 0 | 1 | 53 | 13.3 |
| 2 | Kansas State | 4 | 7 | 7 | 6 | 0 | 0 | 69 | 17.3 |
| 3 | Baylor | 4 | 9 | 5 | 9 | 0 | 0 | 78 | 19.5 |
| 4 | Iowa State | 4 | 12 | 2 | 12 | 0 | 0 | 90 | 22.5 |
| 5 | West Virginia | 4 | 13 | 6 | 11 | 1 | 0 | 109 | 27.3 |
| 6 | Oklahoma | 3 | 11 | 3 | 10 | 0 | 0 | 85 | 28.3 |
| 7 | Texas Tech | 3 | 10 | 6 | 10 | 0 | 0 | 88 | 29.3 |
| 8 | Texas | 4 | 17 | 5 | 16 | 1 | 0 | 135 | 33.8 |
| 9 | Kansas | 4 | 21 | 3 | 21 | 0 | 0 | 156 | 39.0 |
| 10 | TCU | 4 | 23 | 2 | 23 | 0 | 0 | 167 | 41.8 |