2021 Big 12 Conference Leaders Rushing Defense - Games vs. FBS Teams With Non-Winning Record Only through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Baylor | 5 | 162 | 474 | 2.93 | 4 | 32.40 | 94.80 |
| 2 | Oklahoma State | 4 | 131 | 387 | 2.95 | 3 | 32.75 | 96.75 |
| 2 | West Virginia | 4 | 131 | 545 | 4.16 | 4 | 32.75 | 136.25 |
| 4 | Kansas State | 6 | 200 | 739 | 3.70 | 2 | 33.33 | 123.17 |
| 5 | Oklahoma | 6 | 205 | 739 | 3.60 | 7 | 34.17 | 123.17 |
| 6 | Iowa State | 5 | 178 | 573 | 3.22 | 3 | 35.60 | 114.60 |
| 7 | Texas Tech | 5 | 188 | 1024 | 5.45 | 11 | 37.60 | 204.80 |
| 8 | TCU | 4 | 152 | 758 | 4.99 | 9 | 38.00 | 189.50 |
| 9 | Texas | 4 | 159 | 689 | 4.33 | 7 | 39.75 | 172.25 |
| 10 | Kansas | 4 | 183 | 1030 | 5.63 | 12 | 45.75 | 257.50 |