2021 Big 12 Conference Leaders Rushing Defense - When Losing By 15+ Pts through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Long | 1st | 10+ | 20+ | |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Oklahoma State | 1 | 6 | 35 | 5.83 | 0 | 12 | 2 | 1 | 0 |
| 1 | Kansas State | 1 | 16 | 58 | 3.63 | 0 | 14 | 2 | 2 | 0 |
| 3 | Oklahoma | 1 | 9 | 36 | 4.00 | 0 | 33 | 2 | 1 | 1 |
| 3 | Iowa State | 2 | 12 | 58 | 4.83 | 0 | 51 | 1 | 1 | 1 |
| 5 | West Virginia | 3 | 28 | 138 | 4.93 | 1 | 31 | 5 | 4 | 3 |
| 5 | Texas | 3 | 36 | 206 | 5.72 | 2 | 30 | 9 | 5 | 3 |
| 7 | Texas Tech | 4 | 98 | 557 | 5.68 | 5 | 75 | 26 | 16 | 4 |
| 8 | TCU | 5 | 80 | 539 | 6.74 | 7 | 80 | 20 | 12 | 6 |
| 9 | Kansas | 7 | 135 | 969 | 7.18 | 12 | 80 | 44 | 34 | 9 |
| 1st: First Downs; 10+: Rush attempts of 10 or more yards; 20+: Rush attempts of 20 or more yards | ||||||||||