2021 Big 12 Conference Leaders Passing Defense - From Opponent's 1 To 20 Yard Line through 01/10/2022
| Name | G | Att | Comp | Pct. | Yards | TD | Int | Rating | Long | 1st | 15+ | 25+ | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Baylor | 13 | 38 | 22 | 57.9 | 216 | 0 | 4 | 84.60 | 29 | 12 | 7 | 2 |
| 2 | Iowa State | 11 | 34 | 19 | 55.9 | 159 | 0 | 3 | 77.51 | 37 | 5 | 3 | 1 |
| 2 | Kansas State | 12 | 29 | 19 | 65.5 | 257 | 1 | 3 | 130.65 | 81 | 8 | 5 | 3 |
| 4 | Kansas | 9 | 20 | 11 | 55.0 | 134 | 0 | 2 | 91.28 | 28 | 7 | 4 | 1 |
| 4 | Texas Tech | 11 | 44 | 35 | 79.5 | 544 | 0 | 2 | 174.32 | 55 | 17 | 14 | 10 |
| 6 | West Virginia | 11 | 31 | 24 | 77.4 | 221 | 0 | 1 | 130.85 | 42 | 9 | 3 | 1 |
| 7 | Texas | 9 | 25 | 19 | 76.0 | 182 | 0 | 0 | 137.15 | 45 | 8 | 3 | 1 |
| 7 | Oklahoma | 12 | 40 | 27 | 67.5 | 285 | 0 | 0 | 127.35 | 55 | 9 | 4 | 1 |
| 7 | TCU | 10 | 22 | 16 | 72.7 | 316 | 0 | 0 | 193.39 | 75 | 10 | 8 | 6 |
| 7 | Oklahoma State | 13 | 63 | 37 | 58.7 | 469 | 0 | 0 | 121.26 | 77 | 17 | 11 | 6 |
| 1st: First Downs; 15+: Pass completions of 15 or more yards; 25+: Pass completions of 25 or more yards | |||||||||||||