2021 Big 12 Conference Leaders Passing Defense - From Opponent's 40 to Own 40 Yard Line through 01/10/2022
| Name | G | Att | Comp | Pct. | Yards | TD | Int | Rating | Long | 1st | 15+ | 25+ | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Baylor | 14 | 110 | 73 | 66.4 | 749 | 0 | 2 | 119.92 | 35 | 39 | 20 | 4 |
| 2 | Texas Tech | 13 | 141 | 89 | 63.1 | 988 | 2 | 2 | 123.82 | 43 | 42 | 21 | 9 |
| 3 | Kansas | 12 | 89 | 62 | 69.7 | 718 | 1 | 1 | 138.88 | 47 | 36 | 18 | 3 |
| 4 | Texas | 12 | 92 | 62 | 67.4 | 733 | 3 | 2 | 140.72 | 52 | 36 | 13 | 7 |
| 4 | Iowa State | 13 | 110 | 64 | 58.2 | 814 | 4 | 4 | 125.07 | 52 | 34 | 17 | 9 |
| 6 | Oklahoma | 13 | 124 | 85 | 68.5 | 895 | 2 | 5 | 126.44 | 53 | 45 | 21 | 7 |
| 7 | Oklahoma State | 14 | 109 | 70 | 64.2 | 790 | 2 | 0 | 131.16 | 55 | 36 | 17 | 6 |
| 7 | Kansas State | 13 | 95 | 66 | 69.5 | 792 | 0 | 3 | 133.18 | 55 | 38 | 24 | 3 |
| 7 | TCU | 11 | 97 | 60 | 61.9 | 868 | 2 | 2 | 139.70 | 55 | 41 | 17 | 11 |
| 10 | West Virginia | 13 | 97 | 60 | 61.9 | 777 | 2 | 4 | 127.69 | 60 | 30 | 17 | 8 |
| 1st: First Downs; 15+: Pass completions of 15 or more yards; 25+: Pass completions of 25 or more yards | |||||||||||||