2021 Big 12 Conference Leaders All Purpose - Games vs. FBS non-Power 5 Conference Teams Only through 01/10/2022
| Name | Team | Yr | Pos | G | Rush | Recv. | Punt Ret. | Kick Ret. | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | LD Brown | Okla St | SR | RB | 3 | 55 | 9 | 0 | 132 | 22 | 196 | 8.9 | 65.3 |
| 2 | JD Spielman | TCU | SR | WR | 1 | 0 | 54 | 0 | 93 | 6 | 147 | 24.5 | 147.0 |
| 3 | Kenny Logan Jr. | Kansas | JR | S | 1 | 0 | 0 | 0 | 76 | 3 | 76 | 25.3 | 76.0 |
| 4 | Trestan Ebner | Baylor | SR | RB | 2 | 215 | 1 | -1 | 68 | 38 | 283 | 7.4 | 141.5 |
| 5 | Eli Sanders | Iowa State | FR | RB | 1 | 4 | 0 | 0 | 51 | 5 | 55 | 11.0 | 55.0 |
| 6 | Chadarius Townsend | Texas Tech | SR | RB | 2 | 28 | 0 | 0 | 28 | 7 | 56 | 8.0 | 28.0 |
| 7 | Brennan Presley | Okla St | SO | WR | 3 | 1 | 178 | 34 | 26 | 21 | 239 | 11.4 | 79.7 |
| 8 | D'Shawn Jamison | Texas | SR | DB | 2 | 0 | 0 | 11 | 25 | 4 | 36 | 9.0 | 18.0 |
| 9 | Monaray Baldwin | Baylor | FR | WR | 1 | 0 | 0 | 0 | 23 | 2 | 23 | 11.5 | 23.0 |
| 10 | Jamahl Horne | Kansas | JR | WR | 1 | 0 | 0 | 0 | 19 | 1 | 19 | 19.0 | 19.0 |