2021 Big 12 Conference Leaders Tackles - Games in December/January Only through 01/10/2022
| Name | Team | Yr | Pos | G | Solo | Assisted | Total | Total/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Terrel Bernard | Baylor | SR | LB | 2 | 16 | 11 | 27 | 13.50 |
| 1 | Malcolm Rodriguez | Okla St | SR | LB | 2 | 16 | 7 | 23 | 11.50 |
| 3 | Dillon Doyle | Baylor | JR | LB | 2 | 10 | 8 | 18 | 9.00 |
| 3 | Mark Milton | Baylor | JR | CB | 2 | 10 | 0 | 10 | 5.00 |
| 5 | Beau Freyler | Iowa State | FR | DB | 1 | 9 | 6 | 15 | 15.00 |
| 5 | Jabbar Muhammad | Okla St | SO | CB | 2 | 9 | 3 | 12 | 6.00 |
| 5 | JT Woods | Baylor | SR | S | 2 | 9 | 2 | 11 | 5.50 |
| 8 | Jalen Pitre | Baylor | SR | S | 2 | 8 | 4 | 12 | 6.00 |
| 8 | Lance Dixon | WVU | SO | LB | 1 | 8 | 3 | 11 | 11.00 |
| 8 | Jairon McVea | Baylor | SR | S | 2 | 8 | 3 | 11 | 5.50 |
| 8 | Colin Schooler | Texas Tech | SR | LB | 1 | 8 | 1 | 9 | 9.00 |
| 12 | Devin Harper | Okla St | SR | LB | 2 | 7 | 8 | 15 | 7.50 |
| 12 | Jackie Matthews | WVU | JR | CB | 1 | 7 | 0 | 7 | 7.00 |
| 14 | Kolby Harvell-Peel | Okla St | SR | S | 2 | 6 | 5 | 11 | 5.50 |
| 14 | Patrick Fields | Oklahoma | SR | S | 1 | 6 | 3 | 9 | 9.00 |
| 14 | Siaki Ika | Baylor | SO | DT | 2 | 6 | 3 | 9 | 4.50 |
| 14 | Matt Jones | Baylor | SO | LB | 2 | 6 | 2 | 8 | 4.00 |
| 14 | Tanner McCalister | Okla St | SR | S | 2 | 6 | 2 | 8 | 4.00 |
| 14 | Christian Holmes | Okla St | SR | CB | 2 | 6 | 2 | 8 | 4.00 |
| 20 | Brock Martin | Okla St | SR | DE | 2 | 5 | 2 | 7 | 3.50 |
| 20 | Jason Taylor II | Okla St | JR | S | 2 | 5 | 1 | 6 | 3.00 |
| 20 | Rayshad Williams | Texas Tech | JR | DB | 1 | 5 | 0 | 5 | 5.00 |
| 20 | Jarrick Bernard-Converse | Okla St | SR | CB | 2 | 5 | 0 | 5 | 2.50 |
| 24 | O'Rien Vance | Iowa State | SR | LB | 1 | 4 | 5 | 9 | 9.00 |
| 24 | Garmon Randolph | Baylor | SO | OLB | 2 | 4 | 4 | 8 | 4.00 |
| 24 | Woodi Washington | Oklahoma | SO | CB | 1 | 4 | 3 | 7 | 7.00 |
| 24 | Daniel Green | Kansas St | JR | LB | 1 | 4 | 2 | 6 | 6.00 |
| 24 | Josh Chandler-Semedo | WVU | SR | LB | 1 | 4 | 2 | 6 | 6.00 |
| 24 | Cole Maxwell | Baylor | SR | DT | 2 | 4 | 2 | 6 | 3.00 |
| 24 | D.J. Graham | Oklahoma | SO | CB | 1 | 4 | 1 | 5 | 5.00 |
| 24 | Delarrin Turner-Yell | Oklahoma | SR | S | 1 | 4 | 1 | 5 | 5.00 |
| 24 | Daryl Porter Jr. | WVU | FR | CB | 1 | 4 | 1 | 5 | 5.00 |
| 24 | Dadrion Taylor-Demerson | Texas Tech | JR | DB | 1 | 4 | 0 | 4 | 4.00 |
| 24 | Tyree Wilson | Texas Tech | JR | DL | 1 | 4 | 0 | 4 | 4.00 |
| 24 | Charles Woods | WVU | JR | CB | 1 | 4 | 0 | 4 | 4.00 |
| 24 | Dante Stills | WVU | SR | DL | 1 | 4 | 0 | 4 | 4.00 |
| 24 | Kalon Barnes | Baylor | SR | CB | 2 | 4 | 0 | 4 | 2.00 |
| 24 | Bryson Jackson | Baylor | SR | OLB | 2 | 4 | 0 | 4 | 2.00 |
| 39 | Danny Stutsman | Oklahoma | FR | LB | 1 | 3 | 4 | 7 | 7.00 |
| 39 | Craig McDonald | Iowa State | FR | DB | 1 | 3 | 3 | 6 | 6.00 |
| 39 | Justin Broiles | Oklahoma | SR | DB | 1 | 3 | 3 | 6 | 6.00 |
| 39 | Julius Brents | Kansas St | JR | DB | 1 | 3 | 2 | 5 | 5.00 |
| 39 | Riko Jeffers | Texas Tech | SR | LB | 1 | 3 | 2 | 5 | 5.00 |
| 39 | Greg Eisworth II | Iowa State | SR | DB | 1 | 3 | 1 | 4 | 4.00 |
| 39 | Ethan Downs | Oklahoma | FR | DE | 1 | 3 | 1 | 4 | 4.00 |
| 39 | Sean Mahone | WVU | SR | S | 1 | 3 | 1 | 4 | 4.00 |
| 39 | Al Walcott | Baylor | JR | CB | 2 | 3 | 1 | 4 | 2.00 |
| 39 | Jayden Jernigan | Okla St | SO | DT | 2 | 3 | 1 | 4 | 2.00 |
| 39 | Eric Monroe | Texas Tech | SR | DB | 1 | 3 | 0 | 3 | 3.00 |
| 39 | DaMarcus Fields | Texas Tech | SR | DB | 1 | 3 | 0 | 3 | 3.00 |