2021 Big 12 Conference Leaders Passing - Games at Home Only through 01/10/2022
| Name | Team | Yr | Pos | G | Att | Comp | Pct. | Yards | Yards/Att | TD | Int | Rating | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Chandler Morris | TCU | FR | QB | 2 | 42 | 30 | 71.4 | 481 | 11.5 | 3 | 0 | 191.20 | 21.0 | 240.5 |
| 2 | Caleb Williams | Oklahoma | FR | QB | 5 | 81 | 54 | 66.7 | 868 | 10.7 | 11 | 1 | 199.02 | 16.2 | 173.6 |
| 2 | Shane Illingworth | Okla St | SO | QB | 3 | 50 | 28 | 56.0 | 385 | 7.7 | 3 | 1 | 136.48 | 16.7 | 128.3 |
| 2 | Jason Bean | Kansas | JR | QB | 6 | 96 | 58 | 60.4 | 610 | 6.4 | 4 | 1 | 125.46 | 16.0 | 101.7 |
| 5 | Tyler Shough | Texas Tech | JR | QB | 2 | 57 | 38 | 66.7 | 573 | 10.1 | 5 | 2 | 173.05 | 28.5 | 286.5 |
| 5 | Henry Colombi | Texas Tech | SR | QB | 3 | 59 | 34 | 57.6 | 500 | 8.5 | 0 | 2 | 122.04 | 19.7 | 166.7 |
| 5 | Jalon Daniels | Kansas | SO | QB | 3 | 52 | 35 | 67.3 | 354 | 6.8 | 2 | 2 | 129.50 | 17.3 | 118.0 |
| 8 | Brock Purdy | Iowa State | SR | QB | 6 | 176 | 126 | 71.6 | 1403 | 8.0 | 8 | 3 | 150.14 | 29.3 | 233.8 |
| 8 | Skylar Thompson | Kansas St | SR | QB | 6 | 137 | 89 | 65.0 | 1160 | 8.5 | 7 | 3 | 148.56 | 22.8 | 193.3 |
| 8 | Spencer Rattler | Oklahoma | SO | QB | 6 | 141 | 106 | 75.2 | 1093 | 7.8 | 9 | 3 | 157.10 | 23.5 | 182.2 |
| 11 | Jarret Doege | WVU | SR | QB | 6 | 192 | 126 | 65.6 | 1539 | 8.0 | 12 | 4 | 149.42 | 32.0 | 256.5 |
| 11 | Gerry Bohanon | Baylor | JR | QB | 6 | 150 | 96 | 64.0 | 1274 | 8.5 | 11 | 4 | 154.21 | 25.0 | 212.3 |
| 13 | Max Duggan | TCU | JR | QB | 6 | 148 | 93 | 62.8 | 1309 | 8.8 | 9 | 5 | 150.45 | 24.7 | 218.2 |
| 14 | Spencer Sanders | Okla St | JR | QB | 6 | 157 | 98 | 62.4 | 1305 | 8.3 | 9 | 6 | 143.52 | 26.2 | 217.5 |
| 14 | Casey Thompson | Texas | JR | QB | 6 | 139 | 99 | 71.2 | 1215 | 8.7 | 16 | 6 | 174.00 | 23.2 | 202.5 |
Note: To qualify, player must have and have a minimum of 15.0 pass attempts per game played.