2021 Conference USA Leaders Fumbles Lost - Games vs. FBS Power 5 Conference Teams Only through 01/10/2022
| Name | G | Fumbles | Fumbles Lost | Fumble Lost % | |
|---|---|---|---|---|---|
| 1 | UAB | 1 | 0 | 0 | 0 |
| 1 | Old Dominion | 1 | 0 | 0 | 0 |
| 1 | Southern Miss | 1 | 0 | 0 | 0 |
| 1 | FIU | 1 | 1 | 0 | 0.00 |
| 1 | Middle Tennessee State | 1 | 1 | 0 | 0.00 |
| 6 | UTSA | 1 | 1 | 1 | 100.00 |
| 6 | Western Kentucky | 2 | 1 | 1 | 100.00 |
| 6 | Louisiana Tech | 2 | 2 | 1 | 50.00 |
| 6 | North Texas | 1 | 2 | 1 | 50.00 |
| 6 | Rice | 2 | 3 | 1 | 33.33 |
| 6 | Charlotte | 2 | 4 | 1 | 25.00 |
| 12 | Florida Atlantic | 1 | 2 | 2 | 100.00 |