2021 Conference USA Leaders Penalties - Games Lost Only through 01/10/2022
| Name | G | Pen. | Yards | Pen./G | Yards/G | |
|---|---|---|---|---|---|---|
| 1 | UTSA | 2 | 14 | 147 | 7.0 | 73.5 |
| 2 | Western Kentucky | 5 | 36 | 276 | 7.2 | 55.2 |
| 3 | Marshall | 6 | 38 | 316 | 6.3 | 52.7 |
| 4 | Middle Tennessee State | 6 | 39 | 331 | 6.5 | 55.2 |
| 5 | UAB | 4 | 43 | 404 | 10.8 | 101.0 |
| 6 | Florida Atlantic | 7 | 48 | 400 | 6.9 | 57.1 |
| 7 | Charlotte | 7 | 49 | 425 | 7.0 | 60.7 |
| 8 | UTEP | 6 | 51 | 393 | 8.5 | 65.5 |
| 9 | Old Dominion | 7 | 60 | 544 | 8.6 | 77.7 |
| 10 | Louisiana Tech | 9 | 61 | 463 | 6.8 | 51.4 |
| 11 | Rice | 8 | 62 | 505 | 7.8 | 63.1 |
| 12 | FIU | 11 | 64 | 546 | 5.8 | 49.6 |
| 12 | North Texas | 7 | 64 | 590 | 9.1 | 84.3 |
| 14 | Southern Miss | 9 | 84 | 640 | 9.3 | 71.1 |