2021 Conference USA Leaders Tackles For Loss - Games vs. FBS Teams With Winning Record Only through 01/10/2022
| Name | G | TFL | TFL Yards | TFL/G | |
|---|---|---|---|---|---|
| 1 | Marshall | 6 | 50.0 | 200 | 8.33 |
| 2 | Middle Tennessee State | 5 | 28.0 | 106 | 5.60 |
| 3 | Old Dominion | 7 | 39.0 | 132 | 5.57 |
| 4 | UAB | 6 | 32.0 | 133 | 5.33 |
| 4 | Florida Atlantic | 6 | 32.0 | 119 | 5.33 |
| 6 | UTSA | 6 | 31.0 | 138 | 5.17 |
| 7 | North Texas | 7 | 36.0 | 186 | 5.14 |
| 8 | Southern Miss | 5 | 25.0 | 76 | 5.00 |
| 9 | UTEP | 4 | 19.0 | 68 | 4.75 |
| 10 | Western Kentucky | 7 | 33.0 | 117 | 4.71 |
| 11 | FIU | 5 | 21.0 | 64 | 4.20 |
| 12 | Louisiana Tech | 6 | 25.0 | 126 | 4.17 |
| 12 | Rice | 6 | 25.0 | 110 | 4.17 |
| 14 | Charlotte | 4 | 10.0 | 41 | 2.50 |