2021 Conference USA Leaders Opponent Penalties - Games in October Only through 01/10/2022
| Name | G | Pen. | Yards | Pen./G | Yards/G | |
|---|---|---|---|---|---|---|
| 1 | Florida Atlantic | 4 | 38 | 340 | 9.5 | 85.0 |
| 1 | North Texas | 4 | 38 | 307 | 9.5 | 76.8 |
| 3 | Middle Tennessee | 4 | 35 | 302 | 8.8 | 75.5 |
| 3 | Western Kentucky | 5 | 35 | 310 | 7.0 | 62.0 |
| 5 | Marshall | 4 | 34 | 320 | 8.5 | 80.0 |
| 6 | UTEP | 4 | 33 | 278 | 8.3 | 69.5 |
| 7 | Rice | 4 | 30 | 307 | 7.5 | 76.8 |
| 8 | Charlotte | 4 | 28 | 284 | 7.0 | 71.0 |
| 8 | Southern Mississippi | 4 | 28 | 264 | 7.0 | 66.0 |
| 10 | Old Dominion | 4 | 27 | 248 | 6.8 | 62.0 |
| 10 | UTSA | 4 | 27 | 219 | 6.8 | 54.8 |
| 12 | UAB | 4 | 22 | 217 | 5.5 | 54.3 |
| 13 | Florida International | 4 | 21 | 152 | 5.3 | 38.0 |
| 14 | Louisiana Tech | 4 | 17 | 190 | 4.3 | 47.5 |