2021 Conference USA Leaders Sacks Allowed - Games in August/September Only through 01/10/2022
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | Charlotte | 4 | 4.0 | 21 | 1.00 |
| 1 | Marshall | 4 | 4.0 | 31 | 1.00 |
| 3 | UTEP | 4 | 5.0 | 35 | 1.25 |
| 4 | Western Kentucky | 3 | 4.0 | 24 | 1.33 |
| 5 | UTSA | 4 | 6.0 | 31 | 1.50 |
| 5 | Louisiana Tech | 4 | 6.0 | 39 | 1.50 |
| 7 | North Texas | 4 | 7.0 | 39 | 1.75 |
| 8 | FIU | 4 | 8.0 | 72 | 2.00 |
| 9 | UAB | 4 | 9.0 | 63 | 2.25 |
| 10 | Rice | 4 | 10.0 | 52 | 2.50 |
| 11 | Florida Atlantic | 4 | 11.0 | 64 | 2.75 |
| 11 | Old Dominion | 4 | 11.0 | 65 | 2.75 |
| 11 | Middle Tennessee State | 4 | 11.0 | 93 | 2.75 |
| 14 | Southern Miss | 4 | 18.0 | 143 | 4.50 |