2021 Conference USA Leaders Passes Defended - Games in October Only through 01/10/2022
| Name | Team | Yr | Pos | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Roger Cray | ODU | SR | CB | 3 | 1 | 6 | 7 | 2.33 |
| 2 | Zyon Gilbert | FAU | SR | CB | 4 | 1 | 6 | 7 | 1.75 |
| 3 | Reed Blankenship | MTSU | SR | S | 4 | 0 | 6 | 6 | 1.50 |
| 4 | R'Tarriun Johnson | ODU | JR | S | 4 | 2 | 3 | 5 | 1.25 |
| 4 | Praise Amaewhule | UTEP | SO | DE | 4 | 0 | 5 | 5 | 1.25 |
| 6 | Will Ignont | Western Ky | JR | LB | 5 | 1 | 4 | 5 | 1.00 |
| 6 | Gregory Grate | MTSU | JR | S | 4 | 2 | 2 | 4 | 1.00 |
| 6 | Korel Smith | FAU | SR | CB | 4 | 1 | 3 | 4 | 1.00 |
| 6 | Romain Mungin | FAU | SO | CB | 4 | 1 | 3 | 4 | 1.00 |
| 6 | Nazeeh Johnson | Marshall | SR | S | 4 | 1 | 3 | 4 | 1.00 |
| 6 | Miles McCord | Rice | JR | CB | 4 | 1 | 3 | 4 | 1.00 |
| 6 | Teja Young | FAU | SO | S | 4 | 0 | 4 | 4 | 1.00 |
| 6 | Cedric Woods | La Tech | FR | DB | 4 | 0 | 4 | 4 | 1.00 |
| 6 | Micah Abraham | Marshall | SO | DB | 4 | 0 | 4 | 4 | 1.00 |
| 6 | Joe Joe Headen | ODU | SR | S | 4 | 0 | 4 | 4 | 1.00 |
| 16 | Antwon Kincade | Western Ky | SR | DB | 5 | 1 | 3 | 4 | 0.80 |
| 17 | Steven Gilmore | Marshall | JR | DB | 4 | 2 | 1 | 3 | 0.75 |
| 17 | Cory McCoy | Marshall | SR | S | 4 | 2 | 1 | 3 | 0.75 |
| 17 | Naeem Smith | Rice | SR | S | 4 | 2 | 1 | 3 | 0.75 |
| 17 | Jordan Helm | FAU | SR | S | 4 | 1 | 2 | 3 | 0.75 |
| 17 | Dy'vonne Inyang | UTEP | SR | DB | 4 | 1 | 2 | 3 | 0.75 |
| 17 | Clarence Hicks | UTSA | SR | OLB | 4 | 1 | 2 | 3 | 0.75 |
| 17 | Corey Mayfield Jr. | UTSA | SR | CB | 4 | 1 | 2 | 3 | 0.75 |
| 17 | A.J. Brathwaite, Jr. | Western Ky | SO | DB | 4 | 1 | 2 | 3 | 0.75 |
| 17 | Teldrick Ross | MTSU | SO | S | 4 | 0 | 3 | 3 | 0.75 |
| 17 | Trey Creamer | Charlotte | SR | DB | 4 | 0 | 3 | 3 | 0.75 |
| 17 | Tre Hawkins III | ODU | JR | CB | 4 | 0 | 3 | 3 | 0.75 |
| 17 | Gabe Taylor | Rice | FR | DB | 4 | 0 | 3 | 3 | 0.75 |
| 17 | Jordan Dunbar | Rice | FR | CB | 4 | 0 | 3 | 3 | 0.75 |
| 17 | Natrone Brooks | USM | JR | DB | 4 | 0 | 3 | 3 | 0.75 |
| 17 | Breon Hayward | UTEP | JR | LB | 4 | 0 | 3 | 3 | 0.75 |
| 17 | Ken Robinson | UTSA | SO | CB | 4 | 0 | 3 | 3 | 0.75 |
| 17 | Brandon Brown | UTSA | FR | DL | 4 | 0 | 3 | 3 | 0.75 |
| 34 | Geo Howard | Charlotte | SR | CB | 3 | 0 | 2 | 2 | 0.67 |
| 34 | John Davis | N Texas | JR | DB | 3 | 0 | 2 | 2 | 0.67 |
| 34 | Justin Prince | UTEP | JR | DB | 3 | 0 | 2 | 2 | 0.67 |
| 37 | Miguel Edwards | Western Ky | SO | DB | 5 | 0 | 3 | 3 | 0.60 |
| 38 | DQ Thomas | MTSU | SR | LB | 4 | 2 | 0 | 2 | 0.50 |
| 38 | Grayson Cash | UAB | JR | S | 4 | 1 | 1 | 2 | 0.50 |
| 38 | Kyle Harrell | UAB | SR | OLB | 4 | 1 | 1 | 2 | 0.50 |
| 38 | Ahman Ross | FAU | JR | S | 4 | 1 | 1 | 2 | 0.50 |
| 38 | Deidrick Stanley II | MTSU | FR | S | 4 | 1 | 1 | 2 | 0.50 |
| 38 | Eric Scott, Jr. | USM | JR | DB | 4 | 1 | 1 | 2 | 0.50 |
| 38 | Malik Shorts | USM | SO | DB | 4 | 1 | 1 | 2 | 0.50 |
| 38 | Dennis Barnes | UTEP | JR | DB | 4 | 1 | 1 | 2 | 0.50 |
| 38 | Torey Richardson | UTEP | SO | CB | 4 | 1 | 1 | 2 | 0.50 |
| 38 | Jahmal Sam | UTSA | SO | S | 4 | 1 | 1 | 2 | 0.50 |
| 38 | Keondre Swoopes | UAB | JR | S | 4 | 0 | 2 | 2 | 0.50 |
| 38 | Keivie Rose | La Tech | FR | DL | 4 | 0 | 2 | 2 | 0.50 |
| 38 | Ezekiel Barnett | La Tech | SR | LB | 4 | 0 | 2 | 2 | 0.50 |
Note: To qualify, player must have played in 75% of his team's games.