2021 Conference USA Leaders Interceptions - Games vs. Conference Teams Only through 01/10/2022
| Name | Team | Yr | Pos | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Quincy Riley | MTSU | FR | CB | 7 | 4 | 127 | 1 | 0.57 |
| 2 | Naeem Smith | Rice | SR | S | 8 | 4 | 22 | 0 | 0.50 |
| 3 | Grayson Cash | UAB | JR | S | 8 | 3 | 105 | 1 | 0.38 |
| 3 | Beanie Bishop | Western Ky | SO | DB | 8 | 3 | 72 | 1 | 0.38 |
| 5 | Omari Alexander | Western Ky | SR | DB | 9 | 3 | 0 | 0 | 0.33 |
| 5 | Dy'vonne Inyang | UTEP | SR | DB | 6 | 2 | 4 | 0 | 0.33 |
| 5 | Nazeeh Johnson | Marshall | SR | S | 6 | 2 | 0 | 0 | 0.33 |
| 8 | Romain Mungin | FAU | SO | CB | 7 | 2 | 40 | 0 | 0.29 |
| 9 | Joe Joe Headen | ODU | SR | S | 8 | 2 | 89 | 0 | 0.25 |
| 9 | Kevin Wood | N Texas | SO | LB | 8 | 2 | 75 | 0 | 0.25 |
| 9 | Cory McCoy | Marshall | SR | S | 8 | 2 | 65 | 0 | 0.25 |
| 9 | Jay Stanley | USM | SO | DB | 8 | 2 | 61 | 1 | 0.25 |
| 9 | Jaiden Cole | La Tech | JR | DB | 8 | 2 | 57 | 0 | 0.25 |
| 9 | Davion Williams | Western Ky | SO | DB | 8 | 2 | 45 | 1 | 0.25 |
| 9 | Eric Scott, Jr. | USM | JR | DB | 8 | 2 | 23 | 0 | 0.25 |
| 9 | Steven Gilmore | Marshall | JR | DB | 8 | 2 | 22 | 0 | 0.25 |
| 9 | R'Tarriun Johnson | ODU | JR | S | 8 | 2 | 15 | 0 | 0.25 |
| 9 | Gabe Taylor | Rice | FR | DB | 8 | 2 | 13 | 0 | 0.25 |
| 9 | Kirk Lockhart | Rice | SO | S | 8 | 2 | 10 | 0 | 0.25 |
| 9 | Luke Martin | Charlotte | SR | LB | 8 | 2 | 8 | 1 | 0.25 |
| 9 | Korel Smith | FAU | SR | CB | 8 | 2 | -3 | 0 | 0.25 |
| 22 | Antonio Parks | UTSA | SR | S | 9 | 2 | 54 | 0 | 0.22 |
| 22 | Corey Mayfield Jr. | UTSA | SR | CB | 9 | 2 | 49 | 1 | 0.22 |
| 22 | Kahlef Hailassie | Western Ky | SO | DB | 9 | 2 | 14 | 0 | 0.22 |
| 22 | Demetrius Cain | Western Ky | SR | LB | 9 | 2 | 0 | 0 | 0.22 |
| 26 | Marley Cook | MTSU | FR | DT | 6 | 1 | 15 | 0 | 0.17 |
| 27 | DQ Thomas | MTSU | SR | LB | 7 | 1 | 43 | 1 | 0.14 |
| 27 | Roger Cray | ODU | SR | CB | 7 | 1 | 16 | 0 | 0.14 |
| 27 | Christian Gomez | Western Ky | JR | LB | 7 | 1 | 10 | 0 | 0.14 |
| 27 | BeeJay Williamson | La Tech | SO | DB | 7 | 1 | 0 | 0 | 0.14 |
| 27 | Marcus Robitaille | Charlotte | SO | DB | 7 | 1 | 0 | 0 | 0.14 |
| 27 | Lance McMillan | Charlotte | JR | DB | 7 | 1 | 0 | 0 | 0.14 |
| 27 | Jamal Ligon | UTSA | SO | ILB | 7 | 1 | 0 | 0 | 0.14 |
| 27 | Will Ignont | Western Ky | JR | LB | 7 | 1 | 0 | 0 | 0.14 |
| 35 | Teja Young | FAU | SO | S | 8 | 1 | 62 | 1 | 0.13 |
| 35 | Ezekiel Barnett | La Tech | SR | LB | 8 | 1 | 46 | 0 | 0.13 |
| 35 | Natrone Brooks | USM | JR | DB | 8 | 1 | 34 | 1 | 0.13 |
| 35 | Jordan Helm | FAU | SR | S | 8 | 1 | 25 | 0 | 0.13 |
| 35 | Ahman Ross | FAU | JR | S | 8 | 1 | 20 | 0 | 0.13 |
| 35 | Noah Wilder | UAB | SR | LB | 8 | 1 | 18 | 0 | 0.13 |
| 35 | Averie Habas | USM | SO | LB | 8 | 1 | 6 | 1 | 0.13 |
| 35 | Starling Thomas V | UAB | JR | CB | 8 | 1 | 6 | 0 | 0.13 |
| 35 | Eli Neal | Marshall | SO | LB | 8 | 1 | 6 | 0 | 0.13 |
| 35 | Keondre Swoopes | UAB | JR | S | 8 | 1 | 5 | 0 | 0.13 |
| 35 | A.J. Brathwaite, Jr. | Western Ky | SO | DB | 8 | 1 | 5 | 0 | 0.13 |
| 35 | Kyle Harrell | UAB | SR | OLB | 8 | 1 | 2 | 0 | 0.13 |
| 35 | Deeve Harris | ODU | FR | DE | 8 | 1 | 0 | 1 | 0.13 |
| 35 | Zyon Gilbert | FAU | SR | CB | 8 | 1 | 0 | 0 | 0.13 |
| 35 | Richard Dames | FIU | SR | DB | 8 | 1 | 0 | 0 | 0.13 |
| 35 | Gio Richardson | FIU | FR | DB | 8 | 1 | 0 | 0 | 0.13 |
Note: To qualify, player must have played in 75% of his team's games.