2020 Louisville Cardinals Total Defense Game Log through 01/11/2021
| Date | Opponent | Surface | Result | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play |
|---|---|---|---|---|---|---|---|---|
| 09/12/20 | Western Ky. | Turf | W 35-21 | 119 | 129 | 58 | 248 | 4.28 |
| 09/19/20 | 18 Miami (Fla.) | Turf | L 34-47 | 160 | 325 | 60 | 485 | 8.08 |
| 09/26/20 | @ Pittsburgh | Grass | L 20-23 | 156 | 220 | 78 | 376 | 4.82 |
| 10/09/20 | @ Georgia Tech | Grass | L 27-46 | 192 | 258 | 56 | 450 | 8.04 |
| 10/17/20 | @ 4 Notre Dame | Turf | L 7-12 | 232 | 106 | 68 | 338 | 4.97 |
| 10/24/20 | Florida St. | Turf | W 48-16 | 265 | 141 | 81 | 406 | 5.01 |
| 10/31/20 | Virginia Tech | Turf | L 35-42 | 283 | 183 | 61 | 466 | 7.64 |
| 11/14/20 | @ Virginia | Grass | L 17-31 | 165 | 203 | 65 | 368 | 5.66 |
| 11/20/20 | Syracuse | Turf | W 30-0 | 92 | 45 | 41 | 137 | 3.34 |
| 11/28/20 | @ Boston College | Turf | L 27-34 | 188 | 247 | 63 | 435 | 6.90 |
| 12/12/20 | Wake Forest | Turf | W 45-21 | 127 | 224 | 72 | 351 | 4.88 |
| Totals | 1979 | 2081 | 703 | 4060 | 5.78 | |||
| @ : Away, + : Neutral Site | ||||||||