2020 American Athletic Conference Leaders Rushing Defense - Games vs. Ranked Teams Only (AP Poll) through 01/11/2021
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Cincinnati | 2 | 61 | 211 | 3.46 | 3 | 30.50 | 105.50 |
| 2 | Tulsa | 1 | 38 | 151 | 3.97 | 2 | 38.00 | 151.00 |
| 3 | UCF | 3 | 130 | 523 | 4.02 | 7 | 43.33 | 174.33 |
| 4 | Tulane | 1 | 41 | 179 | 4.37 | 1 | 41.00 | 179.00 |
| 5 | Houston | 2 | 63 | 420 | 6.67 | 6 | 31.50 | 210.00 |
| 6 | Navy | 2 | 92 | 429 | 4.66 | 5 | 46.00 | 214.50 |
| 7 | SMU | 2 | 80 | 443 | 5.54 | 6 | 40.00 | 221.50 |
| 8 | USF | 3 | 127 | 697 | 5.49 | 11 | 42.33 | 232.33 |
| 9 | East Carolina | 2 | 69 | 474 | 6.87 | 6 | 34.50 | 237.00 |
| 10 | Memphis | 1 | 41 | 242 | 5.90 | 4 | 41.00 | 242.00 |