2020 Atlantic Coast Conference Leaders Rushing Defense - Games vs. Ranked Teams Only (AP Poll) through 01/11/2021
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Pittsburgh | 4 | 160 | 431 | 2.69 | 6 | 40.00 | 107.75 |
| 2 | Virginia | 4 | 154 | 531 | 3.45 | 6 | 38.50 | 132.75 |
| 3 | Notre Dame | 4 | 115 | 480 | 4.17 | 5 | 28.75 | 120.00 |
| 4 | Georgia Tech | 3 | 115 | 486 | 4.23 | 8 | 38.33 | 162.00 |
| 5 | Clemson | 4 | 139 | 595 | 4.28 | 6 | 34.75 | 148.75 |
| 6 | North Carolina | 4 | 117 | 533 | 4.56 | 10 | 29.25 | 133.25 |
| 7 | North Carolina State | 3 | 134 | 622 | 4.64 | 5 | 44.67 | 207.33 |
| 8 | Boston College | 3 | 119 | 556 | 4.67 | 6 | 39.67 | 185.33 |
| 9 | Wake Forest | 3 | 133 | 647 | 4.86 | 9 | 44.33 | 215.67 |
| 10 | Louisville | 2 | 79 | 392 | 4.96 | 3 | 39.50 | 196.00 |
| 11 | Syracuse | 5 | 204 | 1023 | 5.01 | 14 | 40.80 | 204.60 |
| 12 | Duke | 4 | 168 | 843 | 5.02 | 11 | 42.00 | 210.75 |
| 13 | Florida State | 4 | 163 | 885 | 5.43 | 11 | 40.75 | 221.25 |
| 13 | Virginia Tech | 5 | 213 | 1156 | 5.43 | 15 | 42.60 | 231.20 |
| 15 | Miami (Florida) | 3 | 133 | 943 | 7.09 | 10 | 44.33 | 314.33 |