2020 Big 12 Conference Leaders Total Defense - Games vs. Ranked Teams Only (AP Poll) through 01/11/2021
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | West Virginia | 2 | 415 | 431 | 134 | 846 | 6.31 | 423.0 |
| 2 | Texas | 2 | 329 | 573 | 166 | 902 | 5.43 | 451.0 |
| 3 | Baylor | 3 | 433 | 627 | 194 | 1060 | 5.46 | 353.3 |
| 4 | Kansas | 3 | 643 | 767 | 198 | 1410 | 7.12 | 470.0 |
| 5 | TCU | 3 | 530 | 779 | 178 | 1309 | 7.35 | 436.3 |
| 6 | Texas Tech | 3 | 641 | 910 | 252 | 1551 | 6.15 | 517.0 |
| 7 | Kansas State | 3 | 704 | 960 | 205 | 1664 | 8.12 | 554.7 |
| 8 | Oklahoma State | 5 | 804 | 1153 | 348 | 1957 | 5.62 | 391.4 |
| 9 | Oklahoma | 4 | 639 | 1162 | 298 | 1801 | 6.04 | 450.3 |
| 10 | Iowa State | 5 | 583 | 1255 | 301 | 1838 | 6.11 | 367.6 |