2020 Big 12 Conference Leaders Sacks - Games in December/January Only through 01/11/2021
| Name | Team | Yr | Pos | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Will McDonald IV | Iowa State | SO | DE | 3 | 4.0 | 24 | 1.33 |
| 2 | Isaiah Thomas | Oklahoma | JR | DL | 3 | 3.0 | 22 | 1.00 |
| 3 | Jalen Pitre | Baylor | JR | S | 2 | 2.5 | 21 | 1.25 |
| 4 | Ochaun Mathis | TCU | SO | DE | 2 | 2.0 | 19 | 1.00 |
| 5 | Calvin Bundage | Okla St | SR | LB | 3 | 2.5 | 18 | 0.83 |
| 6 | Nick Channel | Kansas | SO | LB | 1 | 1.0 | 12 | 1.00 |
| 7 | Ronnie Perkins | Oklahoma | JR | DE | 3 | 2.0 | 10 | 0.67 |
| 7 | Josh Landry | Baylor | SO | DT | 1 | 1.0 | 10 | 1.00 |
| 9 | Vernon Broughton | Texas | FR | DL | 1 | 1.0 | 9 | 1.00 |
| 9 | Joseph Ossai | Texas | JR | LB | 1 | 1.0 | 9 | 1.00 |
| 9 | Christian Morgan | Baylor | JR | S | 2 | 1.0 | 9 | 0.50 |
| 9 | Brock Martin | Okla St | JR | DE | 3 | 1.0 | 9 | 0.33 |
| 9 | Cameron Murray | Okla St | SR | DT | 3 | 1.0 | 9 | 0.33 |
| 14 | Tony Bradford Jr. | Texas Tech | SO | DL | 1 | 1.0 | 8 | 1.00 |
| 15 | Colin Schooler | Texas Tech | SR | LB | 1 | 1.5 | 7 | 1.50 |
| 15 | Nik Bonitto | Oklahoma | SO | OLB | 2 | 1.5 | 7 | 0.75 |
| 15 | Dylan Horton | TCU | JR | DE | 2 | 1.0 | 7 | 0.50 |
| 18 | Krishon Merriweather | Texas Tech | JR | LB | 1 | 1.5 | 6 | 1.50 |
| 18 | La'Kendrick Van Zandt | TCU | JR | S | 2 | 1.0 | 6 | 0.50 |
| 18 | Garret Wallow | TCU | SR | LB | 2 | 1.0 | 6 | 0.50 |
| 21 | Wyatt Hubert | Kansas St | JR | DE | 1 | 1.0 | 5 | 1.00 |
| 21 | Trace Ford | Okla St | SO | DE | 2 | 1.0 | 5 | 0.50 |
| 23 | JaQuan Bailey | Iowa State | SR | DE | 3 | 1.0 | 4 | 0.33 |
| 24 | Kolby Harvell-Peel | Okla St | JR | S | 3 | 1.0 | 3 | 0.33 |
| 24 | TJ Franklin | Baylor | SO | DE | 2 | 0.5 | 3 | 0.25 |
| 24 | Tre Sterling | Okla St | JR | S | 2 | 0.5 | 3 | 0.25 |
| 24 | Brian Asamoah | Oklahoma | SO | LB | 3 | 0.5 | 3 | 0.17 |
| 28 | Abram Smith | Baylor | JR | LB | 2 | 1.0 | 1 | 0.50 |