2020 Conference USA Leaders Total Defense - Games in August/September Only through 01/11/2021
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Marshall | 2 | 182 | 348 | 119 | 530 | 4.45 | 265.0 |
| 2 | Florida International | 1 | 219 | 308 | 79 | 527 | 6.67 | 527.0 |
| 3 | Louisiana Tech | 2 | 224 | 670 | 148 | 894 | 6.04 | 447.0 |
| 4 | Charlotte | 1 | 308 | 204 | 71 | 512 | 7.21 | 512.0 |
| 5 | UTSA | 3 | 373 | 1006 | 228 | 1379 | 6.05 | 459.7 |
| 6 | UTEP | 4 | 411 | 1009 | 221 | 1420 | 6.43 | 355.0 |
| 7 | North Texas | 2 | 455 | 824 | 170 | 1279 | 7.52 | 639.5 |
| 8 | Western Kentucky | 2 | 498 | 476 | 151 | 974 | 6.45 | 487.0 |
| 9 | UAB | 3 | 584 | 519 | 209 | 1103 | 5.28 | 367.7 |
| 10 | Middle Tennessee | 3 | 668 | 587 | 230 | 1255 | 5.46 | 418.3 |
| 11 | Southern Mississippi | 3 | 753 | 723 | 220 | 1476 | 6.71 | 492.0 |