2016 Conference USA Leaders Total Defense - Games at Home Only through 01/09/2017
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Western Kentucky | 7 | 589 | 1695 | 474 | 2284 | 4.82 | 326.3 |
| 2 | Louisiana Tech | 5 | 649 | 1101 | 366 | 1750 | 4.78 | 350.0 |
| 3 | Southern Mississippi | 6 | 748 | 867 | 369 | 1615 | 4.38 | 269.2 |
| 4 | Charlotte | 6 | 777 | 1738 | 446 | 2515 | 5.64 | 419.2 |
| 5 | Old Dominion | 6 | 785 | 1169 | 408 | 1954 | 4.79 | 325.7 |
| 6 | UTSA | 6 | 848 | 1555 | 425 | 2403 | 5.65 | 400.5 |
| 7 | Middle Tennessee | 5 | 909 | 1347 | 392 | 2256 | 5.76 | 451.2 |
| 8 | North Texas | 6 | 1048 | 1362 | 412 | 2410 | 5.85 | 401.7 |
| 9 | Rice | 6 | 1214 | 1543 | 411 | 2757 | 6.71 | 459.5 |
| 10 | Marshall | 7 | 1222 | 1802 | 485 | 3024 | 6.24 | 432.0 |
| 11 | Florida Atlantic | 6 | 1300 | 1799 | 439 | 3099 | 7.06 | 516.5 |
| 12 | Florida International | 7 | 1351 | 1697 | 458 | 3048 | 6.66 | 435.4 |
| 13 | UTEP | 7 | 1400 | 1346 | 473 | 2746 | 5.81 | 392.3 |