2022 Mid-American Conference Leaders Total Defense - Games in November Only through 01/09/2023
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Ohio | 4 | 235 | 984 | 244 | 1219 | 5.00 | 304.8 |
| 2 | Akron | 2 | 244 | 362 | 141 | 606 | 4.30 | 303.0 |
| 3 | Toledo | 3 | 382 | 543 | 205 | 925 | 4.51 | 308.3 |
| 4 | Eastern Michigan | 3 | 440 | 532 | 186 | 972 | 5.23 | 324.0 |
| 5 | Kent State | 4 | 586 | 968 | 326 | 1554 | 4.77 | 388.5 |
| 6 | Western Michigan | 4 | 608 | 623 | 255 | 1231 | 4.83 | 307.8 |
| 7 | Miami (Ohio) | 3 | 659 | 669 | 201 | 1328 | 6.61 | 442.7 |
| 8 | Bowling Green | 4 | 669 | 930 | 294 | 1599 | 5.44 | 399.8 |
| 9 | Buffalo | 3 | 674 | 584 | 195 | 1258 | 6.45 | 419.3 |
| 10 | Ball State | 4 | 705 | 904 | 324 | 1609 | 4.97 | 402.3 |
| 11 | Northern Illinois | 4 | 747 | 888 | 290 | 1635 | 5.64 | 408.8 |
| 12 | Central Michigan | 4 | 824 | 717 | 299 | 1541 | 5.15 | 385.3 |