2022 American Athletic Conference Leaders Opponent First Downs - Games vs. FBS Teams With Winning Record Only through 01/09/2023
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Navy | 8 | 48 | 81 | 7 | 136 | 17.0 |
| 2 | Houston | 6 | 58 | 73 | 11 | 142 | 23.7 |
| 2 | Cincinnati | 6 | 72 | 56 | 14 | 142 | 23.7 |
| 4 | Temple | 6 | 56 | 83 | 7 | 146 | 24.3 |
| 5 | Memphis | 6 | 49 | 88 | 10 | 147 | 24.5 |
| 6 | Tulsa | 7 | 68 | 70 | 10 | 148 | 21.1 |
| 7 | East Carolina | 8 | 55 | 106 | 8 | 169 | 21.1 |
| 7 | SMU | 8 | 74 | 87 | 8 | 169 | 21.1 |
| 9 | UCF | 8 | 53 | 105 | 19 | 177 | 22.1 |
| 10 | South Florida | 8 | 95 | 112 | 7 | 214 | 26.8 |
| 11 | Tulane | 10 | 95 | 120 | 12 | 227 | 22.7 |