2022 Big 12 Conference Leaders Opponent First Downs - Games in August/September Only through 01/09/2023
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Oklahoma State | 3 | 17 | 37 | 3 | 57 | 19.0 |
| 2 | TCU | 3 | 19 | 36 | 5 | 60 | 20.0 |
| 3 | Iowa State | 4 | 20 | 33 | 8 | 61 | 15.3 |
| 3 | Texas Tech | 4 | 20 | 34 | 7 | 61 | 15.3 |
| 5 | Baylor | 4 | 21 | 38 | 9 | 68 | 17.0 |
| 6 | West Virginia | 4 | 22 | 40 | 6 | 68 | 17.0 |
| 7 | Kansas | 4 | 26 | 51 | 13 | 90 | 22.5 |
| 8 | Texas | 4 | 28 | 54 | 6 | 88 | 22.0 |
| 9 | Kansas State | 4 | 33 | 34 | 4 | 71 | 17.8 |
| 10 | Oklahoma | 4 | 42 | 43 | 10 | 95 | 23.8 |