2022 Big 12 Conference Leaders Passes Defended - Games vs. Conference Teams Only through 01/09/2023
| Name | Team | Yr | Pos | G | Int. | Passes Broken Up | Passes Defended | Passes Defended/G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Tre'Vius Hodges-Tomlinson | TCU | SR | CB | 10 | 3 | 10 | 13 | 1.30 |
| 1 | Josh Newton | TCU | JR | CB | 10 | 1 | 10 | 11 | 1.10 |
| 3 | Cobee Bryant | Kansas | SO | CB | 8 | 3 | 8 | 11 | 1.38 |
| 3 | Jabbar Muhammad | Okla St | JR | CB | 9 | 1 | 8 | 9 | 1.00 |
| 5 | T.J. Tampa | Iowa State | JR | DB | 9 | 1 | 7 | 8 | 0.89 |
| 5 | Jerrin Thompson | Texas | JR | DB | 9 | 0 | 7 | 7 | 0.78 |
| 7 | Rayshad Williams | Texas Tech | SR | DB | 9 | 1 | 6 | 7 | 0.78 |
| 7 | Josh Hayes | Kansas St | SR | S | 10 | 0 | 6 | 6 | 0.60 |
| 9 | C.J. Coldon | Oklahoma | SR | DB | 8 | 4 | 5 | 9 | 1.13 |
| 9 | DaShaun White | Oklahoma | SR | LB | 9 | 2 | 5 | 7 | 0.78 |
| 9 | Malik Dunlap | Texas Tech | SR | DB | 8 | 1 | 5 | 6 | 0.75 |
| 9 | Woodi Washington | Oklahoma | JR | DB | 9 | 1 | 5 | 6 | 0.67 |
| 9 | Lorando Johnson | Baylor | SO | CB | 9 | 0 | 5 | 5 | 0.56 |
| 14 | Jason Taylor II | Okla St | SR | S | 9 | 6 | 4 | 10 | 1.11 |
| 14 | Julius Brents | Kansas St | SR | CB | 10 | 4 | 4 | 8 | 0.80 |
| 14 | Bud Clark | TCU | SO | S | 10 | 4 | 4 | 8 | 0.80 |
| 14 | Christian Morgan | Baylor | SR | S | 9 | 3 | 4 | 7 | 0.78 |
| 14 | Devin Lemear | Baylor | FR | S | 9 | 2 | 4 | 6 | 0.67 |
| 14 | Dadrion Taylor-Demerson | Texas Tech | SR | DB | 9 | 2 | 4 | 6 | 0.67 |
| 14 | Malachi Ruffin | WVU | JR | DB | 9 | 2 | 4 | 6 | 0.67 |
| 14 | D'Shawn Jamison | Texas | SR | DB | 8 | 1 | 4 | 5 | 0.63 |
| 14 | Austin Moore | Kansas St | JR | LB | 10 | 1 | 4 | 5 | 0.50 |
| 14 | Key Lawrence | Oklahoma | JR | DB | 8 | 0 | 4 | 4 | 0.50 |
| 14 | Tayvonn Kyle | Iowa State | SR | DB | 9 | 0 | 4 | 4 | 0.44 |
| 14 | DeMarvion Overshown | Texas | SR | LB | 9 | 0 | 4 | 4 | 0.44 |
| 14 | Jordan Jefferson | WVU | JR | DL | 9 | 0 | 4 | 4 | 0.44 |
| 27 | Billy Bowman Jr. | Oklahoma | SO | DB | 7 | 2 | 3 | 5 | 0.71 |
| 27 | Kendal Daniels | Okla St | FR | S | 9 | 2 | 3 | 5 | 0.56 |
| 27 | Millard Bradford | TCU | SR | S | 8 | 1 | 3 | 4 | 0.50 |
| 27 | Mark Milton | Baylor | SR | CB | 9 | 1 | 3 | 4 | 0.44 |
| 27 | Anthony Johnson Jr. | Iowa State | SR | DB | 9 | 1 | 3 | 4 | 0.44 |
| 27 | Craig Young | Kansas | JR | LB | 9 | 1 | 3 | 4 | 0.44 |
| 27 | O.J. Burroughs | Kansas | SO | S | 9 | 1 | 3 | 4 | 0.44 |
| 27 | Kenny Logan Jr. | Kansas | SR | S | 9 | 1 | 3 | 4 | 0.44 |
| 27 | Reggie Pearson Jr. | Texas Tech | SR | DB | 9 | 1 | 3 | 4 | 0.44 |
| 27 | Ryan Watts | Texas | JR | DB | 9 | 1 | 3 | 4 | 0.44 |
| 27 | Trace Ford | Okla St | JR | DE | 6 | 0 | 3 | 3 | 0.50 |
| 27 | Matt Jones | Baylor | JR | LB | 8 | 0 | 3 | 3 | 0.38 |
| 27 | TJ Franklin | Baylor | SR | DL | 9 | 0 | 3 | 3 | 0.33 |
| 27 | Will McDonald IV | Iowa State | SR | DE | 9 | 0 | 3 | 3 | 0.33 |
| 27 | Kalon Gervin | Kansas | JR | CB | 9 | 0 | 3 | 3 | 0.33 |
| 27 | Korie Black | Okla St | JR | CB | 9 | 0 | 3 | 3 | 0.33 |
| 27 | Jalen Redmond | Oklahoma | JR | DL | 9 | 0 | 3 | 3 | 0.33 |
| 27 | T'Vondre Sweat | Texas | SR | DL | 9 | 0 | 3 | 3 | 0.33 |
| 27 | Ovie Oghoufo | Texas | SR | EDG | 9 | 0 | 3 | 3 | 0.33 |
| 27 | Jasir Cox | WVU | SR | SPR | 9 | 0 | 3 | 3 | 0.33 |
| 27 | Ekow Boye-Doe | Kansas St | SR | CB | 10 | 0 | 3 | 3 | 0.30 |
| 27 | Jacob Parrish | Kansas St | FR | CB | 10 | 0 | 3 | 3 | 0.30 |
| 27 | Abe Camara | TCU | JR | S | 10 | 0 | 3 | 3 | 0.30 |
| 50 | Jaylan Ford | Texas | JR | LB | 9 | 4 | 2 | 6 | 0.67 |