2022 Conference USA Leaders Tackles For Loss - Games vs. FBS Power 5 Conference Teams Only through 01/09/2023
| Name | G | TFL | TFL Yards | TFL/G | |
|---|---|---|---|---|---|
| 1 | Middle Tennessee | 1 | 8.0 | 41 | 8.00 |
| 2 | Western Kentucky | 2 | 13.0 | 47 | 6.50 |
| 3 | Charlotte | 2 | 12.0 | 33 | 6.00 |
| 4 | UTSA | 1 | 5.0 | 17 | 5.00 |
| 5 | Louisiana Tech | 2 | 9.0 | 35 | 4.50 |
| 6 | Florida Atlantic | 1 | 4.0 | 11 | 4.00 |
| 6 | UAB | 1 | 4.0 | 5 | 4.00 |
| 8 | UTEP | 1 | 3.0 | 11 | 3.00 |
| 9 | Rice | 1 | 2.0 | 5 | 2.00 |