2022 Conference USA Leaders Sacks - Games vs. FBS Teams With Non-Winning Record Only through 01/09/2023
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | Middle Tennessee | 7 | 28.0 | 193 | 4.00 |
| 2 | UTEP | 8 | 18.0 | 128 | 2.25 |
| 3 | Western Kentucky | 8 | 15.0 | 101 | 1.88 |
| 4 | UAB | 7 | 14.0 | 95 | 2.00 |
| 5 | North Texas | 6 | 12.0 | 74 | 2.00 |
| 5 | Florida International | 7 | 12.0 | 74 | 1.71 |
| 7 | Rice | 6 | 11.0 | 94 | 1.83 |
| 7 | Florida Atlantic | 5 | 11.0 | 59 | 2.20 |
| 9 | UTSA | 7 | 10.0 | 78 | 1.43 |
| 10 | Charlotte | 6 | 8.0 | 48 | 1.33 |
| 11 | Louisiana Tech | 6 | 7.0 | 45 | 1.17 |