2022 Conference USA Leaders Sacks - Games vs. Non-Conference Teams Only through 01/09/2023
| Name | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|
| 1 | Middle Tennessee | 5 | 18.0 | 136 | 3.60 |
| 2 | Western Kentucky | 6 | 19.0 | 110 | 3.17 |
| 3 | UTSA | 5 | 12.0 | 64 | 2.40 |
| 4 | Rice | 5 | 10.0 | 61 | 2.00 |
| 5 | Florida International | 4 | 7.0 | 46 | 1.75 |
| 6 | North Texas | 5 | 7.0 | 45 | 1.40 |
| 7 | UAB | 5 | 10.0 | 37 | 2.00 |
| 8 | Florida Atlantic | 4 | 7.0 | 31 | 1.75 |
| 9 | UTEP | 4 | 6.0 | 27 | 1.50 |
| 10 | Charlotte | 4 | 5.0 | 26 | 1.25 |
| 11 | Louisiana Tech | 4 | 5.0 | 22 | 1.25 |