2021 Wyoming Cowboys Opponent Penalty Split Stats through 01/10/2022
| Split | G | Pen. | Yards | Pen./G | Yards/G |
|---|---|---|---|---|---|
| All Games | 13 | 62 | 511 | 4.8 | 39.3 |
| at Home | 6 | 28 | 244 | 4.7 | 40.7 |
| on Road/Neutral Site | 7 | 34 | 267 | 4.9 | 38.1 |
| in Wins | 7 | 40 | 337 | 5.7 | 48.1 |
| in Losses | 6 | 22 | 174 | 3.7 | 29.0 |
| vs. Conference | 8 | 30 | 264 | 3.8 | 33.0 |
| vs. Non-Conference | 5 | 32 | 247 | 6.4 | 49.4 |
| vs. Ranked (AP) | 1 | 1 | 15 | 1.0 | 15.0 |
| vs. Unranked (AP) | 12 | 61 | 496 | 5.1 | 41.3 |
| vs. FBS (I-A) | 12 | 57 | 479 | 4.8 | 39.9 |
| vs. FCS (I-AA) | 1 | 5 | 32 | 5.0 | 32.0 |
| vs. FBS Winning | 5 | 17 | 152 | 3.4 | 30.4 |
| vs. FBS Non-Winning | 7 | 40 | 327 | 5.7 | 46.7 |
| vs. FBS Power 5 | 0 | 0 | 0 | - | - |
| vs. FBS non-Power 5 | 12 | 57 | 479 | 4.8 | 39.9 |
| in August/September | 4 | 20 | 152 | 5.0 | 38.0 |
| in October | 4 | 16 | 129 | 4.0 | 32.3 |
| in November | 4 | 14 | 135 | 3.5 | 33.8 |
| in December/January | 1 | 12 | 95 | 12.0 | 95.0 |