2021 Vanderbilt Commodores Total Defense Split Stats through 01/10/2022
| Split | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G |
|---|---|---|---|---|---|---|---|
| All Games | 12 | 2317 | 3171 | 813 | 5488 | 6.75 | 457.3 |
| at Home | 7 | 1393 | 1831 | 488 | 3224 | 6.61 | 460.6 |
| on Road/Neutral Site | 5 | 924 | 1340 | 325 | 2264 | 6.97 | 452.8 |
| in Wins | 2 | 391 | 569 | 151 | 960 | 6.36 | 480.0 |
| in Losses | 10 | 1926 | 2602 | 662 | 4528 | 6.84 | 452.8 |
| vs. Conference | 8 | 1543 | 2249 | 547 | 3792 | 6.93 | 474.0 |
| vs. Non-Conference | 4 | 774 | 922 | 266 | 1696 | 6.38 | 424.0 |
| vs. Ranked (AP) | 3 | 618 | 799 | 199 | 1417 | 7.12 | 472.3 |
| vs. Unranked (AP) | 9 | 1699 | 2372 | 614 | 4071 | 6.63 | 452.3 |
| vs. FBS (I-A) | 11 | 2138 | 3036 | 754 | 5174 | 6.86 | 470.4 |
| vs. FCS (I-AA) | 1 | 179 | 135 | 59 | 314 | 5.32 | 314.0 |
| vs. FBS Winning | 6 | 1078 | 1733 | 413 | 2811 | 6.81 | 468.5 |
| vs. FBS Non-Winning | 5 | 1060 | 1303 | 341 | 2363 | 6.93 | 472.6 |
| vs. FBS Power 5 | 9 | 1747 | 2467 | 603 | 4214 | 6.99 | 468.2 |
| vs. FBS non-Power 5 | 2 | 391 | 569 | 151 | 960 | 6.36 | 480.0 |
| in August/September | 4 | 833 | 882 | 262 | 1715 | 6.55 | 428.8 |
| in October | 5 | 824 | 1625 | 368 | 2449 | 6.65 | 489.8 |
| in November | 3 | 660 | 664 | 183 | 1324 | 7.23 | 441.3 |
| in December/January | 0 | 0 | 0 | 0 | 0 | - | - |