2021 USC Trojans Total Defense Split Stats through 01/10/2022
| Split | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G |
|---|---|---|---|---|---|---|---|
| All Games | 12 | 1983 | 2902 | 767 | 4885 | 6.37 | 407.1 |
| at Home | 7 | 1264 | 2025 | 462 | 3289 | 7.12 | 469.9 |
| on Road/Neutral Site | 5 | 719 | 877 | 305 | 1596 | 5.23 | 319.2 |
| in Wins | 4 | 373 | 989 | 256 | 1362 | 5.32 | 340.5 |
| in Losses | 8 | 1610 | 1913 | 511 | 3523 | 6.89 | 440.4 |
| vs. Conference | 9 | 1579 | 2105 | 557 | 3684 | 6.61 | 409.3 |
| vs. Non-Conference | 3 | 404 | 797 | 210 | 1201 | 5.72 | 400.3 |
| vs. Ranked (AP) | 3 | 517 | 795 | 208 | 1312 | 6.31 | 437.3 |
| vs. Unranked (AP) | 9 | 1466 | 2107 | 559 | 3573 | 6.39 | 397.0 |
| vs. FBS (I-A) | 12 | 1983 | 2902 | 767 | 4885 | 6.37 | 407.1 |
| vs. FCS (I-AA) | 0 | 0 | 0 | 0 | 0 | - | - |
| vs. FBS Winning | 7 | 1480 | 1682 | 470 | 3162 | 6.73 | 451.7 |
| vs. FBS Non-Winning | 5 | 503 | 1220 | 297 | 1723 | 5.80 | 344.6 |
| vs. FBS Power 5 | 9 | 1579 | 2105 | 557 | 3684 | 6.61 | 409.3 |
| vs. FBS non-Power 5 | 3 | 404 | 797 | 210 | 1201 | 5.72 | 400.3 |
| in August/September | 4 | 629 | 935 | 252 | 1564 | 6.21 | 391.0 |
| in October | 4 | 557 | 1020 | 261 | 1577 | 6.04 | 394.3 |
| in November | 3 | 709 | 770 | 202 | 1479 | 7.32 | 493.0 |
| in December/January | 1 | 88 | 177 | 52 | 265 | 5.10 | 265.0 |