2021 Louisville Cardinals Scoring Offense Game Log through 01/10/2022
| Date | Opponent | Surface | Result | TD | FG | 1XP | 2XP | Safety | Points |
|---|---|---|---|---|---|---|---|---|---|
| 09/06/21 | + 11 Mississippi | Turf | L 24-43 | 3 | 1 | 3 | 0 | 0 | 24 |
| 09/11/21 | Eastern Ky. | Turf | W 30-3 | 4 | 1 | 3 | 0 | 0 | 30 |
| 09/17/21 | UCF | Turf | W 42-35 | 6 | 0 | 6 | 0 | 0 | 42 |
| 09/25/21 | @ Florida St. | Grass | W 31-23 | 4 | 1 | 4 | 0 | 0 | 31 |
| 10/02/21 | @ 15 Wake Forest | Turf | L 34-37 | 4 | 2 | 4 | 0 | 0 | 34 |
| 10/09/21 | Virginia | Turf | L 33-34 | 3 | 4 | 3 | 0 | 0 | 33 |
| 10/23/21 | Boston College | Turf | W 28-14 | 4 | 0 | 4 | 0 | 0 | 28 |
| 10/30/21 | @ 20 North Carolina St. | Grass | L 13-28 | 1 | 2 | 1 | 0 | 0 | 13 |
| 11/06/21 | 14 Clemson | Turf | L 24-30 | 3 | 1 | 3 | 0 | 0 | 24 |
| 11/13/21 | Syracuse | Turf | W 41-3 | 5 | 2 | 5 | 0 | 0 | 41 |
| 11/18/21 | @ Duke | Grass | W 62-22 | 9 | 0 | 8 | 0 | 0 | 62 |
| 11/27/21 | 18 Kentucky | Turf | L 21-52 | 3 | 0 | 3 | 0 | 0 | 21 |
| 12/28/21 | + Air Force | Turf | L 28-31 | 4 | 0 | 4 | 0 | 0 | 28 |
| Totals | 53 | 14 | 51 | 0 | 0 | 411 | |||
| @ : Away, + : Neutral Site | |||||||||