2021 National Leaders Interceptions - Games in August/September Only through 01/10/2022
| Name | Team | Yr | Pos | G | Int. | Yards | TD | Int./G | |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Riley Moss | Iowa | SR | DB | 4 | 2 | 85 | 2 | 0.50 |
| 1 | Chad Muma | Wyoming | SR | LB | 4 | 2 | 68 | 2 | 0.50 |
| 3 | Tyric LeBeauf | Boise St | JR | CB | 4 | 3 | 128 | 1 | 0.75 |
| 3 | Bennett Williams | Oregon | JR | S | 4 | 3 | 92 | 1 | 0.75 |
| 3 | Ja'Quan McMillian | ECU | SO | CB | 4 | 3 | 43 | 1 | 0.75 |
| 3 | Max Melton | Rutgers | FR | DB | 3 | 2 | 46 | 1 | 0.67 |
| 3 | David Carter Jr. | EMU | FR | DB | 4 | 2 | 115 | 1 | 0.50 |
| 3 | Christopher Smith | Georgia | SR | DB | 4 | 2 | 94 | 1 | 0.50 |
| 3 | Leon O'Neal Jr. | Texas A&M | SR | DB | 4 | 2 | 85 | 1 | 0.50 |
| 3 | Keondre Swoopes | UAB | JR | S | 4 | 2 | 66 | 1 | 0.50 |
| 3 | Ronnie Hickman | Ohio State | SO | SAF | 4 | 2 | 65 | 1 | 0.50 |
| 3 | BeeJay Williamson | La Tech | SO | DB | 4 | 2 | 62 | 1 | 0.50 |
| 3 | Zion Williams | Troy | JR | CB | 4 | 2 | 38 | 1 | 0.50 |
| 3 | Roger McCreary | Auburn | SR | CB | 4 | 2 | 35 | 1 | 0.50 |
| 3 | Kyu Blu Kelly | Stanford | JR | CB | 4 | 2 | 31 | 1 | 0.50 |
| 3 | Teja Young | FAU | SO | S | 4 | 2 | 22 | 1 | 0.50 |
| 3 | Manny Walker | Temple | SR | DE | 4 | 2 | 11 | 1 | 0.50 |
| 3 | Daniel Scott | California | SR | S | 4 | 2 | 8 | 1 | 0.50 |
| 3 | Ja'Cquez Williams | La-Monroe | SR | LB | 3 | 1 | 96 | 1 | 0.33 |
| 3 | Justin Wright | Tulsa | JR | LB | 3 | 1 | 55 | 1 | 0.33 |
| 3 | Davyn Flenord | USA | JR | CB | 3 | 1 | 48 | 1 | 0.33 |
| 3 | Andrew Aleki | SDSU | SR | LB | 3 | 1 | 26 | 1 | 0.33 |
| 3 | Jamon Dumas-Johnson | Georgia | FR | LB | 3 | 1 | 20 | 1 | 0.33 |
| 3 | Tyrell Ajian | Kentucky | SR | DB | 4 | 1 | 95 | 1 | 0.25 |
| 3 | Alex Hogan | Houston | JR | CB | 4 | 1 | 91 | 1 | 0.25 |
| 3 | Marquis Waters | Texas Tech | SR | DB | 4 | 1 | 72 | 1 | 0.25 |
| 3 | Kris Moncrief | La-Lafytte | JR | LB | 4 | 1 | 67 | 1 | 0.25 |
| 3 | Jack Kiser | Notre Dame | SO | LB | 4 | 1 | 66 | 1 | 0.25 |
| 3 | Jaylin Alderman | Louisville | FR | LB | 4 | 1 | 66 | 1 | 0.25 |
| 3 | Damani Staley | S Carolina | SR | LB | 4 | 1 | 63 | 1 | 0.25 |
| 3 | Cameron Martinez | Ohio State | FR | SAF | 4 | 1 | 61 | 1 | 0.25 |
| 3 | Jordan Burch | S Carolina | SO | EDG | 4 | 1 | 61 | 1 | 0.25 |
| 3 | Clark Phillips III | Utah | FR | CB | 4 | 1 | 54 | 1 | 0.25 |
| 3 | Keyon Blankenbaker | Wyoming | SR | N | 4 | 1 | 50 | 1 | 0.25 |
| 3 | Kevin Henry | Tulane | SR | LB | 4 | 1 | 49 | 1 | 0.25 |
| 3 | Drew White | Notre Dame | SR | LB | 4 | 1 | 48 | 1 | 0.25 |
| 3 | Teldrick Ross | MTSU | SO | S | 4 | 1 | 44 | 1 | 0.25 |
| 3 | Greg Johnson | USC | SR | S | 4 | 1 | 37 | 1 | 0.25 |
| 3 | Smoke Monday | Auburn | SR | S | 4 | 1 | 36 | 1 | 0.25 |
| 3 | Trey Baldwin | La Tech | SR | LB | 4 | 1 | 35 | 1 | 0.25 |
| 3 | Damarri Mathis | Pittsburgh | SR | DB | 4 | 1 | 35 | 1 | 0.25 |
| 3 | John Saunders Jr. | Miami (Oh) | FR | DB | 4 | 1 | 32 | 1 | 0.25 |
| 3 | Solon Page III | Tennessee | SR | LB | 4 | 1 | 31 | 1 | 0.25 |
| 3 | Darren Anders | BGSU | JR | LB | 4 | 1 | 27 | 1 | 0.25 |
| 3 | Josh Thompson | Texas | SR | DB | 4 | 1 | 27 | 1 | 0.25 |
| 3 | Chris McDonald | Toledo | SO | CB | 4 | 1 | 27 | 1 | 0.25 |
| 3 | Jahmin Muse | BC | SR | DB | 4 | 1 | 22 | 1 | 0.25 |
| 3 | JT Woods | Baylor | SR | S | 4 | 1 | 20 | 1 | 0.25 |
| 3 | Devonni Reed | CMU | JR | DB | 4 | 1 | 20 | 1 | 0.25 |
| 3 | Jesse Luketa | Penn State | SR | DE | 4 | 1 | 16 | 1 | 0.25 |
| 3 | Riko Jeffers | Texas Tech | SR | LB | 4 | 1 | 13 | 1 | 0.25 |