2021 Independent Leaders Total Offense - Games vs. Ranked Teams Only (AP Poll) through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Army | 1 | 416 | 179 | 83 | 595 | 7.17 | 595.0 |
| 2 | Notre Dame | 2 | 126 | 766 | 163 | 892 | 5.47 | 446.0 |
| 3 | BYU | 3 | 519 | 736 | 196 | 1255 | 6.40 | 418.3 |
| 4 | Liberty | 2 | 371 | 379 | 152 | 750 | 4.93 | 375.0 |
| 5 | New Mexico State | 4 | 205 | 934 | 281 | 1139 | 4.05 | 284.8 |
| 6 | Massachusetts | 1 | 42 | 167 | 58 | 209 | 3.60 | 209.0 |
| 7 | Connecticut | 2 | 61 | 276 | 125 | 337 | 2.70 | 168.5 |