2021 Independent Leaders Rushing - Games vs. Ranked Teams Only (AP Poll) through 01/10/2022
| Name | Team | Yr | Pos | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Tyler Allgeier | BYU | SO | RB | 3 | 64 | 353 | 5.52 | 4 | 21.33 | 117.67 |
| 2 | Jakobi Buchanan | Army | JR | RB | 1 | 7 | 14 | 2.00 | 2 | 7.00 | 14.00 |
| 3 | Tyhier Tyler | Army | JR | QB | 1 | 15 | 104 | 6.93 | 1 | 15.00 | 104.00 |
| 3 | Anthony Adkins | Army | SO | RB | 1 | 10 | 93 | 9.30 | 1 | 10.00 | 93.00 |
| 3 | Shedro Louis | Liberty | SO | RB | 2 | 12 | 117 | 9.75 | 1 | 6.00 | 58.50 |
| 3 | Jaren Hall | BYU | SO | QB | 2 | 16 | 117 | 7.31 | 1 | 8.00 | 58.50 |
| 3 | Malik Willis | Liberty | JR | QB | 2 | 47 | 99 | 2.11 | 1 | 23.50 | 49.50 |
| 3 | Kyren Williams | Notre Dame | SO | RB | 1 | 13 | 45 | 3.46 | 1 | 13.00 | 45.00 |
| 3 | Brandon Walters | Army | SR | RB | 1 | 4 | 41 | 10.25 | 1 | 4.00 | 41.00 |
| 3 | Juwaun Price | NMSU | FR | RB | 4 | 36 | 105 | 2.92 | 1 | 9.00 | 26.25 |
| 3 | Tyler Lytle | U Mass | SR | QB | 1 | 9 | -13 | -1.44 | 1 | 9.00 | -13.00 |