2021 Mid-American Conference Leaders Total Offense - Games vs. Unranked Teams Only (AP Poll) through 01/10/2022
| Name | G | Rush Yards | Pass Yards | Plays | Total Yards | Yards/Play | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Kent State | 13 | 3403 | 3240 | 988 | 6643 | 6.72 | 511.0 |
| 2 | Central Michigan | 13 | 2329 | 3400 | 968 | 5729 | 5.92 | 440.7 |
| 3 | Northern Illinois | 13 | 3218 | 2577 | 951 | 5795 | 6.09 | 445.8 |
| 4 | Eastern Michigan | 13 | 1541 | 3417 | 910 | 4958 | 5.45 | 381.4 |
| 5 | Buffalo | 12 | 2283 | 2583 | 906 | 4866 | 5.37 | 405.5 |
| 6 | Ball State | 13 | 1699 | 2699 | 884 | 4398 | 4.98 | 338.3 |
| 7 | Miami (Ohio) | 12 | 1750 | 3512 | 806 | 5262 | 6.53 | 438.5 |
| 8 | Western Michigan | 11 | 2497 | 2750 | 805 | 5247 | 6.52 | 477.0 |
| 9 | Toledo | 12 | 2434 | 2856 | 797 | 5290 | 6.64 | 440.8 |
| 10 | Bowling Green | 12 | 1228 | 2578 | 777 | 3806 | 4.90 | 317.2 |
| 11 | Akron | 11 | 1387 | 2457 | 711 | 3844 | 5.41 | 349.5 |
| 12 | Ohio | 11 | 2136 | 2071 | 693 | 4207 | 6.07 | 382.5 |