2021 Mid-American Conference Leaders Rushing Offense - Games vs. Unranked Teams Only (AP Poll) through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Kent State | 13 | 606 | 3403 | 5.62 | 36 | 46.62 | 261.77 |
| 1 | Northern Illinois | 13 | 613 | 3218 | 5.25 | 36 | 47.15 | 247.54 |
| 3 | Buffalo | 12 | 539 | 2283 | 4.24 | 30 | 44.92 | 190.25 |
| 4 | Toledo | 12 | 440 | 2434 | 5.53 | 28 | 36.67 | 202.83 |
| 5 | Western Michigan | 11 | 510 | 2497 | 4.90 | 27 | 46.36 | 227.00 |
| 6 | Eastern Michigan | 13 | 455 | 1541 | 3.39 | 26 | 35.00 | 118.54 |
| 7 | Ohio | 11 | 406 | 2136 | 5.26 | 20 | 36.91 | 194.18 |
| 8 | Central Michigan | 13 | 520 | 2329 | 4.48 | 18 | 40.00 | 179.15 |
| 9 | Ball State | 13 | 444 | 1699 | 3.83 | 17 | 34.15 | 130.69 |
| 10 | Bowling Green | 12 | 370 | 1228 | 3.32 | 15 | 30.83 | 102.33 |
| 11 | Miami (Ohio) | 12 | 407 | 1750 | 4.30 | 14 | 33.92 | 145.83 |
| 12 | Akron | 11 | 392 | 1387 | 3.54 | 8 | 35.64 | 126.09 |