2021 Mid-American Conference Leaders Sacks - Games vs. Ranked Teams Only (AP Poll) through 01/10/2022
| Name | Team | Yr | Pos | G | Sacks | Sack Yards | Sacks/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Bryce Dugan | Ohio | JR | DL | 1 | 1.0 | 19 | 1.00 |
| 2 | Terrance Taylor | Toledo | JR | OLB | 1 | 2.0 | 17 | 2.00 |
| 3 | Ralph Holley | W Mich | SR | DL | 2 | 1.0 | 16 | 0.50 |
| 4 | Ali Fayad | W Mich | SR | DL | 2 | 1.0 | 14 | 0.50 |
| 5 | Lonnie Phelps | Miami (Oh) | SO | DL | 1 | 1.0 | 12 | 1.00 |
| 6 | Jaylen Kelly-Powell | Akron | JR | S | 1 | 1.0 | 8 | 1.00 |
| 6 | Quinyon Mitchell | Toledo | FR | CB | 1 | 1.0 | 8 | 1.00 |
| 8 | Ryan Johnson | Akron | SO | DL | 1 | 1.0 | 7 | 1.00 |
| 9 | Jonathan Jones | Toledo | SR | LB | 1 | 1.0 | 5 | 1.00 |
| 10 | Mike Brown | Miami (Oh) | SR | DB | 1 | 1.0 | 4 | 1.00 |
| 10 | Nate Givhan | Toledo | JR | OLB | 1 | 1.0 | 4 | 1.00 |
| 12 | Braden Fiske | W Mich | SO | DL | 2 | 1.0 | 3 | 0.50 |
| 13 | Jamal Hines | Toledo | JR | OLB | 1 | 0.5 | 2 | 0.50 |
| 14 | Desjuan Johnson | Toledo | JR | DE | 1 | 0.5 | 1 | 0.50 |