2021 Big Ten Conference Leaders Rushing Offense - Games vs. Unranked Teams Only (AP Poll) through 01/10/2022
| Name | G | Att | Yards | Avg. | TD | Att/G | Yards/G | |
|---|---|---|---|---|---|---|---|---|
| 1 | Wisconsin | 10 | 459 | 2455 | 5.35 | 24 | 45.90 | 245.50 |
| 2 | Michigan | 10 | 439 | 2256 | 5.14 | 29 | 43.90 | 225.60 |
| 3 | Nebraska | 7 | 293 | 1503 | 5.13 | 23 | 41.86 | 214.71 |
| 4 | Ohio State | 9 | 299 | 1836 | 6.14 | 20 | 33.22 | 204.00 |
| 5 | Minnesota | 11 | 501 | 2182 | 4.36 | 24 | 45.55 | 198.36 |
| 6 | Michigan State | 10 | 386 | 1962 | 5.08 | 18 | 38.60 | 196.20 |
| 7 | Illinois | 11 | 443 | 2019 | 4.56 | 12 | 40.27 | 183.55 |
| 8 | Northwestern | 9 | 360 | 1381 | 3.84 | 11 | 40.00 | 153.44 |
| 9 | Maryland | 9 | 317 | 1339 | 4.22 | 18 | 35.22 | 148.78 |
| 10 | Rutgers | 9 | 362 | 1288 | 3.56 | 19 | 40.22 | 143.11 |
| 11 | Indiana | 7 | 252 | 866 | 3.44 | 10 | 36.00 | 123.71 |
| 12 | Iowa | 12 | 444 | 1454 | 3.27 | 17 | 37.00 | 121.17 |
| 13 | Penn State | 8 | 279 | 969 | 3.47 | 7 | 34.88 | 121.13 |
| 14 | Purdue | 9 | 284 | 800 | 2.82 | 5 | 31.56 | 88.89 |