2021 Big Ten Conference Leaders First Downs - Games vs. Conference Teams Only through 01/10/2022
| Name | G | Rush | Pass | Penalty | Total | Total/G | |
|---|---|---|---|---|---|---|---|
| 1 | Ohio State | 9 | 76 | 150 | 12 | 238 | 26.4 |
| 2 | Purdue | 9 | 40 | 158 | 16 | 214 | 23.8 |
| 3 | Maryland | 9 | 74 | 115 | 15 | 204 | 22.7 |
| 4 | Michigan | 10 | 108 | 95 | 17 | 220 | 22.0 |
| 5 | Nebraska | 9 | 76 | 100 | 13 | 189 | 21.0 |
| 6 | Minnesota | 9 | 99 | 72 | 17 | 188 | 20.9 |
| 7 | Wisconsin | 9 | 102 | 69 | 13 | 184 | 20.4 |
| 8 | Penn State | 9 | 56 | 107 | 10 | 173 | 19.2 |
| 9 | Michigan State | 9 | 65 | 89 | 16 | 170 | 18.9 |
| 10 | Iowa | 10 | 63 | 88 | 19 | 170 | 17.0 |
| 11 | Rutgers | 9 | 81 | 56 | 12 | 149 | 16.6 |
| 12 | Northwestern | 9 | 71 | 66 | 9 | 146 | 16.2 |
| 13 | Illinois | 9 | 74 | 58 | 13 | 145 | 16.1 |
| 14 | Indiana | 9 | 58 | 56 | 17 | 131 | 14.6 |