2021 Atlantic Coast Conference Leaders Opponent Penalties - Games vs. FBS Teams With Non-Winning Record Only through 01/10/2022
| Name | G | Pen. | Yards | Pen./G | Yards/G | |
|---|---|---|---|---|---|---|
| 1 | Clemson | 6 | 55 | 408 | 9.2 | 68.0 |
| 2 | Miami (Florida) | 6 | 48 | 445 | 8.0 | 74.2 |
| 2 | Florida State | 6 | 48 | 432 | 8.0 | 72.0 |
| 4 | Wake Forest | 9 | 68 | 625 | 7.6 | 69.4 |
| 4 | Boston College | 8 | 61 | 505 | 7.6 | 63.1 |
| 6 | Virginia | 6 | 42 | 404 | 7.0 | 67.3 |
| 7 | Pittsburgh | 7 | 48 | 423 | 6.9 | 60.4 |
| 7 | Duke | 8 | 55 | 466 | 6.9 | 58.3 |
| 9 | Virginia Tech | 7 | 46 | 400 | 6.6 | 57.1 |
| 10 | Georgia Tech | 5 | 32 | 311 | 6.4 | 62.2 |
| 11 | North Carolina State | 7 | 44 | 383 | 6.3 | 54.7 |
| 12 | North Carolina | 5 | 28 | 272 | 5.6 | 54.4 |
| 12 | Louisville | 5 | 28 | 218 | 5.6 | 43.6 |
| 14 | Syracuse | 6 | 13 | 120 | 2.2 | 20.0 |